A. Gelal, P. Jacob, Lisa Yu
Aug 1, 1999
Citations
6
Influential Citations
90
Citations
Quality indicators
Journal
Clinical Pharmacology & Therapeutics
Abstract
Menthol is widely used in a variety of commercial products and foods, but its clinical pharmacology is not well studied. To determine the disposition kinetics and to examine subjective and cardiovascular effects of menthol, we conducted a crossover placebo‐controlled study that compared pure menthol versus placebo, along with an uncontrolled exposure to menthol in food or beverage. A novel assay for the measurement of menthol in biological fluids was also developed.