J. D. Christensen
Apr 1, 1982
Citations
0
Influential Citations
11
Citations
Quality indicators
Journal
Contact Dermatitis
Abstract
Diethyldithiocarbamate chelates nickel and accelerates its excretion in the urine. Disulfiram (Antabuse®) splits into two molecules of sodium diethyldithiocarbamate after absorption. Oral administration of disulfiram tablets starting with 50 mg a day with a gradual increase in dosage to 100 mg not more than twice a day readily cleared the eczema in three patients with severe and long‐standing nickel contact dermatitis.