Hao Shi, Cuirong Sun, Yuan-jiang Pan
Apr 1, 2004
Citations
0
Influential Citations
1
Citations
Journal
Acta Crystallographica Section E: Crystallographic Communications
Abstract
Kamebacetal A, or (1S*,2S*,8S*,9R*,11R*,15S*,16S*,18R*)-15,18-dihydroxy-16-methoxy-12,12-dimethyl-6-methylene-17-oxapentacyclo[7.6.2.15,8.01,11.02,8]octadecan-7-one, C21H30O5, is a natural diterpenoid which has cytotoxic and antibacterial activity. The molecule contains five six-membered rings and one five-membered ring. Ring A adopts a chair conformation, rings B, C, E and F adopt boat conformations, and ring D adopts an envelope conformation. The conjugated α-methylenecyclopentanone is the active part of the molecule due to ring strain.