G. Appendino, F. Borrelli, R. Capasso
Oct 7, 2003
Citations
1
Influential Citations
10
Citations
Quality indicators
Journal
Journal of agricultural and food chemistry
Abstract
Three new diterpenoids belonging to the clerodane (2-3) and halimane (4) structural types have been isolated from the bark of Croton eluteria Bennet, commonly known as cascarilla. Their structures have been fully characterized by spectroscopic means. Cascarilla extract and its major component, cascarillin, were found to significantly increase histamine-induced gastric acid secretion in the mouse stomach. These preliminary results provide the first rationale for the use of cascarilla in bitter preparations aimed at improving digestion.