Haoqian Miao, N. Shevchenko, Andrew L. Otsuki
Sep 17, 2020
Citations
0
Influential Citations
5
Citations
Journal
ChemSusChem
Abstract
Biobased 5-(chloromethyl)furoate and 5-methylfuroate esters can be deprotonated to function as furylogous lithium enolates, and the former can also undergo zinc insertion to access Reformatsky-type chemistry. Carbon nucleophilicity represents hitherto little-explored reactivity in these key carbohydrate-derived platform molecules, expanding their synthetic utility and potentially opening up new sustainable product markets, e.g. in epoxy resins or biobased dyes.