D. Sigman, A. Spassky
1989
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0
Influential Citations
5
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Journal
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Abstract
1,10-Phenanthroline-copper ion is an efficient chemical nuclease which makes single-stranded nicks in DNA at physiological pH’s and temperatures. In addition to serving as a reliable footprinting reagent, it is useful for defining functionally important sequence-dependent conformational variability of DNA and protein-induced structural changes in DNA.