H. Brice, J. Clayden
Mar 30, 2009
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0
Influential Citations
18
Citations
Journal
Chemical communications
Abstract
Isonicotinamides carrying N-furanylmethyl, N-pyrrolylalkyl or N-thiophenylmethyl substituents at nitrogen undergo cyclisation induced by an electrophile, giving spirocyclic compounds or doubly spirocyclic compounds in which both the nucleophilic and electrophilic heterocycles are dearomatised.