A. Schoonjans, L. Roosens, W. Dewals
Jan 15, 2022
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0
Influential Citations
3
Citations
Quality indicators
Journal
Epilepsia
Abstract
This study was undertaken to determine the plasma concentration and pharmacokinetic variability of fenfluramine (FFA) and its main active metabolite norfenfluramine (norFFA) in relation to the prevalence of adverse effects in patients with refractory epilepsy treated with FFA. In addition, the interaction with concomitant antiseizure medications including stiripentol (STP) is studied.