Varsha P. Gajbhiye, R. Kale, K. Vilhekar
Sep 1, 2016
Citations
0
Influential Citations
5
Citations
Quality indicators
Journal
Journal of Medical Society
Abstract
Background: Antimicrobial agents (AMAs) are the most commonly prescribed drugs for lower respiratory tract infections (LRTIs). This study was conducted to evaluate the pattern of prescription and AMAs use in LRTI. Aims: This study was conducted to evaluate the pattern of prescription and AMAs use in Pediatric Intensive Care Unit (PICU) for LRTIs patients of Rural Tertiary Care Teaching Hospital. Materials and Methods: This is prospective, observational study undertaken in a pediatric patient in PICU in tertiary care hospital. Prescriptions of 65 patients of age group 1-12 years diagnosed with (LRTIs) years admitted in PICU of a Rural Tertiary Care Teaching Hospital were studied. Positive blood samples were studies for common microorganisms, their sensitivity, and resistance to AMAs. Settings and Design: The study was a prospective, observational study carried out by collecting prescriptions of patients admitted in PICU diagnosed as LRTI clinically. Statistical Analysis Used: The obtained data were subjected to descriptive statistical analysis using Microsoft Excel. Results: Of 65 patients admitted in PICU of LRTI, 12 patients were of mild-moderate pneumonia, three patients were of bronchiolitis, ten patients were of croup, three patients were of bronchitis, and 37 patients were of severe pneumonia. The most frequently prescribed AMAs were a combination of cephalosporin and aminoglycosides. The most common organism isolated was streptococcus pneumonia sensitive to meropenem in 84.6%, resistant to ampicillin in 92.3%, amoxicillin in 92.3%, and cloxacillin in 92.3% of cases. Conclusions: This study has given an insight into utilization pattern of AMAs in LRTI prescribing on which future intervention studies may be based to promote rational drug use.