B. Lesser, Nicholas Bruchovsky
Aug 1, 1974
Citations
0
Influential Citations
36
Citations
Journal
The Biochemical journal
Abstract
If 5alpha-dihydrotestosterone (17beta-hydroxy-5alpha-androstan-3-one) is administered to castrated rats before prostatic atrophy has commenced, secretory activity of the prostate is stimulated, but not proliferation. Once the number of cells has fallen below normal, hormone induces proliferation until the normal cellular complement has been restored; then proliferation ceases, but secretory activity is stimulated.