R. S. Ping, J. G. White, L. Spear
Jun 1, 1957
Citations
0
Influential Citations
6
Citations
Journal
Oral surgery, oral medicine, and oral pathology
Abstract
D YCLONINE hydrochloride, a new and different chemical compound with local anesthetic properties, has come to our attention and has been studied to determine its usefulness as a topical anesthetic for dentistry. These observations have proved this new drug to have most of the properties which an ideal topical anesthetic should have : (1) potency (comparable with cocaine) ; (2) low sensitization potential; (3) no apparent incompatibilities with other local anesthetic agents; (4) safety, even if absorbed; (5) stability in usable form; and (6) it is not injurious to tissues, its use being free from escharotic, astringent, or caustic changes. In addition, it has the added advantage of a potent antiseptic action. 1, ~ A topical anesthetic should be rapid in its onset. While the action of dyclonine begins within about one minute, good, deep, penetrating anesthesia needed for SOlnC procedures (for example, the t, pening of an abscess) requires three to six minutes; however, the duration of one hour or more is a definite advantage.