J. Nauta, J. Roodenburg, P. Nikkels
Sep 1, 1996
Citations
1
Influential Citations
40
Citations
Quality indicators
Journal
Head & Neck
Abstract
The carcinogen 4‐nitroquinoline 1‐oxide (4NQO) has been used in several studies concerning experimental oral carcinogenesis to induce squamous cell carcinoma in the palatal mucosa of rats, whereas limited attention has been paid to preceding premalignant mucosal changes. The aim of this study was to describe the macroscopic and microscopic changes of the rat palatal mucosa treated with 4NQO as a function of the application time of this carcinogen.