T. Takagi, Y. Naito, T. Okuda
Jul 1, 2010
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0
Influential Citations
12
Citations
Quality indicators
Journal
Journal of Gastroenterology and Hepatology
Abstract
Background and Aims: Ecabet sodium (ES) is a gastric mucosal protective and ulcer‐healing agent. Recently enema therapy with ES was found to be effective for the treatment of human ulcerative colitis as well as experimental colitis in an animal model. Whereas ES possesses potential as a novel treatment for ulcerative colitis, its precise mechanism of action remains to be elucidated. In this study, we investigated the therapeutic efficacy of ES in an experimental rat model of colitis, and evaluated the restitution of intestinal epithelial cells treated with ES in vitro.