H. Mehrabi, Farzaneh Alizadeh-bami, Azam Meydani
Feb 21, 2021
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0
Influential Citations
3
Citations
Journal
Arkivoc
Abstract
The synthesis of 1,2,5-trisubstituted and 4-amino-1,2,5-tetrasubstituted imidazoles was demonstrated via a two-step cyclo-condensation reaction of aryl amines, carbonitriles, and ethyl bromopyruvate or aryl amines and arylglyoxals in ethanol heated under reflux in the presence of iron (III) chloride (FeCl3), and disodium phosphate (Na2HPO4) as catalysts, respectively. All the products were obtained in good to excellent yields and their structures were established from their spectroscopic data.