S. Patil, D. Nagargoje
Mar 25, 2022
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Journal
Research Journal of Chemistry and Environment
Abstract
We are herein reporting a new ecofriendly, convenient and facile method for the synthesis of 2-aryl-1- arylmethyl-1H-benzo[d]imidazoles using sodium hypochlorite. Various imidazole derivatives were prepared from reaction of o-phenylenediamine with substituted aryl and heteroaryl aldehydes in aqueous ethanol at ambient temperature in one step with good to excellent yield. Easy reaction conditions, use of aqueous medium, easy isolation and purification of products make this method superior to other known methods.