B. Hansen, B. Sörbo
Aug 1, 1961
Citations
1
Influential Citations
2
Citations
Journal
Acta Radiologica
Abstract
Materials. The sodium salts of sulfocysteine and aminoethyl thiophosphoric acid (sodium hydrogen S(2-aminoethyl phosphorothioate) were synthesized by previously described methods (SORBO 1958, AKERFELDT 1959). The S-(3-aminopropyl) thiosulfuric acid was prepared according to the directions given by BRETSCHNEIDER (1950) for the synthesis of the aminoethyl ester, except for the fact that the propyl compound was recrystallized from water-ethanol. (Anal. calculated for C3HloN03S2: C 21.0, H 5.27. Found: C 20.8, H 5.5). The S-(2-aminoethyl) ethanethiosulfonate hydrobromide was prepared as follows: 4.98 g sodium ethanethiosulfonate and 6.15 g 2-bromoethylammonium bromide were boiled for 5 hours in 30 ml isopropanol, and left over night. The precipitated sodium bromide was filtered off and washed with a few millilitres isopropanol. Diethyl ether was gradually added to the combined filtrate and washing, whereupon light brown crystals were obtained. As the product was contaminated with sodium bromide, it was treated with