A. Naimark, D. Brodovsky, R. Cherniack
Mar 1, 1960
Citations
0
Influential Citations
26
Citations
Quality indicators
Journal
The American journal of medicine
Abstract
Abstract The effect of a new carbonic anhydrase inhibitor, dichlorphenamide, has been studied in fifteen patients with respiratory insufficiency. All but one showed clinical improvement. In most cases marked improvement in arterial blood gas tension was associated with an increased alveolar ventilation. This improvement has been sustained during prolonged administration of the drug. Possible mechanisms of action of this drug have been investigated and discussed.