Y. Ohashi, Y. Chijiiwa, Koichiro Suzuki
Feb 15, 1999
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Journal
Journal of Bacteriology
Abstract
ABSTRACT 3-Methoxybenzamide (3-MBA), which is known to be an inhibitor of ADP-ribosyltransferase, inhibits cell division in Bacillus subtilis, leading to filamentation and eventually lysis of cells. Our genetic analysis of 3-MBA-resistant mutants indicated that the primary target of the drug is the cell division system involving FtsZ function during both vegetative growth and sporulation.