M. Fahey, S. Rupp, C. Canfell
Nov 1, 1985
Citations
1
Influential Citations
60
Citations
Quality indicators
Journal
British journal of anaesthesia
Abstract
Patients with renal failure and undergoing a cadaver renal transplant were found to have plasma concentrations of laudanosine, following the administration of a single bolus dose of atracurium 0.5 mg kg-1, higher than those found in patients without renal failure. Since laudanosine is a known central nervous system stimulant in a variety of animal species, its actions should be investigated further in man, and particularly in patients with renal failure.