E. DiMango, Daniel B. Spielman, J. Overdevest
Sep 28, 2020
Citations
2
Influential Citations
17
Citations
Quality indicators
Journal
International Forum of Allergy & Rhinology
Abstract
Elexacaftor/tezacaftor/ivacaftor is a highly effective modulator that improves function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein, resulting in improved pulmonary function in patients with cystic fibrosis (CF). We hypothesize that improvements in lung function are associated with improvements in health‐related quality of life and sinonasal health. The aim of this study is to measure the effect of elexacaftor/tezacaftor/ivacaftor on patient‐reported sinonasal and overall quality of life, and to determine the relationship between changes in these 2 outcome measures.