W. M. Ment, Helen S. Naviasky
Oct 1, 1974
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Influential Citations
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Journal
Journal of pharmaceutical sciences
Abstract
Standard recoveries averaging 89.9% are reported for the NF XIII brompheniramine maleate tablet assay procedure, which employs UV comparison of unidentical sample and standard molecular species in the same medium. The data presented indicate that these low assay values are attributable to the chromophoric properties of the maleic acid moiety and its ability to protonate the α-pyridyl chromophore of the brompheniramine molecule in a neutral organic solvent.