Yue Liu, L. Liang, Wen-li Ma
Mar 1, 2006
Citations
0
Influential Citations
3
Citations
Quality indicators
Journal
Nan fang yi ke da xue xue bao = Journal of Southern Medical University
Abstract
OBJECTIVE To study the effect of the S-bioallethrin on human lymphocytes by microarray technique. METHODS The changes of normal human lymphocytes treated with S-bioallethrin were examined with light microscope, flow cytometry, electron microscope, DNA ladder and microarray techniques. RESULTS Morphological study showed that the lymphocytes underwent apoptosis after S-bioallethrin exposure, which as further confirmed by the expression changes of 346 genes. CONCLUSION S-bioallethrin can induce apoptosis of normal human lymphocytes and changes in their gene expression profiles.