V. Novikov, L. Kovaleva
1997
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0
Influential Citations
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Quality indicators
Journal
Eksperimental'naia i klinicheskaia farmakologiia
Abstract
An open craniocerebral trauma was simulated in rat experiments. Oxidative phosphorylation in the brain mitochondria was studied by polygraphy 24 h after the trauma. It was found that trauma to the brain leads to inhibition of respiration in mitochondria in various metabolic states. Nooglutil in a dose of 50 mg/kg prevents these changes. Nooglutil is more effective than picamilon (500 mg/kg) and piriditol (100 mg/kg).