J. W. Harrison, J. Madonia
Aug 1, 1970
Citations
0
Influential Citations
34
Citations
Journal
Oral surgery, oral medicine, and oral pathology
Abstract
Abstract Parachlorophenol is currently used in endodontic therapy in a 35 per cent concentration as camphorated parachlorophenol. There is no scientific evidence that a 35 per cent concentration is the optimum concentration for the antimicrobial effectiveness of this drug. This study determined that a concentration of less than 1 per cent is effective in vitro against a variety of the microorganisms commonly found in infected root canals. These results, therefore, question the necessity for using the 35 per cent concentration. It is suggested that a reduced concentration of parachlorophenol in aqueous and other vehicles be further investigated in vitro and in vivo for possible future clinical use.