A. Kakita, J. Blanchard, J. Fortner
Dec 1, 1975
Citations
0
Influential Citations
16
Citations
Quality indicators
Journal
Transplantation
Abstract
The immunosuppressive effects of prostaglandin E1 and procarbazine hydrochloride were compared in a vascularized organ xenograft model. Hamster-to-rat cardiac grafts were used. Both procarbazine hydrochloride and prostaglandin E1 prolonged survival of the xenograft. Prostaglandin E1 had the additional feature of coincident suppression of hemagglutination titer to hamster red cells. Prostaglandin E1 was somewhat less effective than procarbazine hydrochloride.