Elizabeth Estevez-Fregoso, E. Farfán-García, Itzel H García-Coronel
Jan 8, 2021
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Influential Citations
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Quality indicators
Journal
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements
Abstract
BACKGROUND The number of known boron-containing compounds (BCCs) is increasing due to their identification in nature and innovative synthesis procedures. Their effects on the fungal kingdom are interesting, and some of their mechanisms of action have recently been elucidated. METHODS In this review, scientific reports from relevant chemistry and biomedical databases were collected and analyzed. RESULTS It is notable that several BCC actions in fungi induce social and economic benefits for humans. In fact, boric acid was traditionally used for multiple purposes, but some novel synthetic BCCs are effective antifungal agents, particularly in their action against pathogen species, and some were recently approved for use in humans. Moreover, most reports testing BCCs in fungal species suggest a limiting effect of these compounds on some vital reactions. CONCLUSIONS New BCCs have been synthesized and tested for innovative technological and biomedical emerging applications, and new interest is developing for discovering new strategic compounds that can act as environmental or wood protectors, as well as antimycotic agents that let us improve food acquisition and control some human infections.