H. Shinyama, T. Kawamura, M. Iwamoto
Sep 1, 1997
Citations
0
Influential Citations
4
Citations
Quality indicators
Journal
Journal of Pharmacy and Pharmacology
Abstract
AE0047 [4‐(4‐benzhydrylpiperazino)phenethyl methyl 1,4‐dihydro‐2,6‐dimethyl‐4‐(3‐nitrophenyl)‐3,5‐pyridine dicarboxylate dihydrochloride] is a new dihydropyridine calcium antagonist with protective effects against cerebral ischaemia and the occurrence of stroke in several animal models. We investigated the effects of AE0047 on focal ischaemia induced by middle cerebral artery occlusion in stroke‐prone spontaneously hypertensive rats.