G. Costa, Kenneth Lyles, L. Ullrich
Sep 1, 1976
Citations
1
Influential Citations
23
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Quality indicators
Journal
Cancer
Abstract
14C Tripalmitin was administered intraperitoneally to control mice and to mice bearing subcutaneous Krebs‐2 carcinoma. The rate of excretion of 14CO2 was studied. The presence of a tumor induced a greater than 80% suppression of the formation of 14CO2 within 24 hours from the implantation of the tumor, thus allowing unambiguous identification of the tumor‐bearing mice. When cancer patients were studied, along with normal volunteers and patients with non‐neoplastic diseases, 14CO2 excretion data could be used to identify the cancer patients with an overall accuracy of 84%.