Scott J. Webster, Christina A. Wilson, Chih-Hung Lee
Oct 1, 2011
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Influential Citations
32
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Quality indicators
Journal
British Journal of Pharmacology
Abstract
BACKGROUND Dimebolin (latrepirdine), a compound with multiple potential drug targets, is being evaluated in clinical trials for the treatment of Alzheimer's disease (AD) and preliminary results suggest it can slow the disease process. There is also evidence that dimebolin directly improves aspects of cognition. Here we examined the acute effect of dimebolin on components of working memory in non‐human primates, young adult (11–17 years old) and aged (20–31 years old) rhesus macaques.