M. Marlasca, B. Valiés, M. Riva
1992
Citations
1
Influential Citations
13
Citations
Journal
Diseases of Aquatic Organisms
Abstract
Subchronic exposures to sublethal concentrations of the synthetic, metal-complex dye C.I. Acid Violet 66 and its azo compound C.I. Acid Red 217 did not cause severe histological damage to rainbow trout Oncorhynchus mykiss. Fish exposed to C.I. Acid Violet 66 for 30 d exhibited the most pronounced morphological alterations, which included spongiosis of the gill tissue and degeneration of chloride cells. Both dyes triggered adaptative responses which involved granulocytes, macrophages and granular cells in the gill, and melanomacrophages in the kidney, liver and spleen. Hepatocytes displayed altered endoplasmic reticulurn after treatment. Frequencies of rnicronucleated peripheral erythrocytes did not increase following dye treatment, suggesting that these chemicals, at least at the doses tested, are not genotoxic following a 30 d exposure.