D. Ceylan, A. Aksoy, T. Ertekin
Apr 1, 2018
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2
Influential Citations
32
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Quality indicators
Journal
Journal of Cancer Research and Therapeutics
Abstract
Objective: The aim of study was to investigate anticancer effect of Viburnum opulus (VO) on Ehrlich ascites carcinoma (EAC) bearing mice that treated with different concentrations of VO. Materials and Methods: For tumor transplantation; mice were inoculated with 1 × 106 EAC cells intraperitoneally and than divided into five groups (n = 9). Two hours after inoculation; experimental groups were treated daily with VO extract at doses of 1000 mg/kg, 2000 mg/kg, 4000 mg/kg. Results: Extracts obtained from gilaburu juice can have hinder effect on tumor cell growth. Conclusion: As far as we known, this is the first study about in vivo antitumoral activity of VOon Ehrlich ascites tumor model, and consequently VO extract exhibited anticancer activity against EAC-bearing mice.