A. Koutnik, D. D'Agostino, B. Egan
Apr 1, 2019
Citations
3
Influential Citations
51
Citations
Journal
Trends in Endocrinology & Metabolism
Abstract
The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) are the subject of renewed interest given recently established pleiotropic effects regulating inflammation, oxidative stress, and gene expression. Anticatabolic effects of β-hydroxybutyrate have recently been demonstrated in human skeletal muscle under inflammatory insult, thereby expanding upon the wide-ranging therapeutic applications of nutritional ketosis.