Luo Xian-hu
2012
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Quality indicators
Journal
China Pharmacy
Abstract
OBJECTIVE:To investigate the effects of levamlodipine besylate on left ventricle diastolic function and left ventricular hypertrophy in patients with primary hypertension.METHODS:100 primary hypertension patients with left ventricle diastolic function and left ventricular hypertrophy checked by echocardiogram were randomized into treatment group and control group.Treatment group were given levamlodipine besylate and control group were given compound hypotensive tablets after 3 months and 6 months of treatment.Above indicators were rechecked and compared in pairwise comparison.RESULTS:Compared with before treatment,both left ventricle diastolic function and ventricular hypertrophy index of primary hypertension patients of 2 groups were improved significantly after treatment(P0.05).But treatment group were better than control group,there was statistical significance(P0.05).Compared with 3 months of treatment,the above index of treatment group were further improved after 6 months of treatment,there was statistical significance(P0.05).But control group had no statistical significance(P0.05).CONCLUSION:Levamlodipine besylate can improve left ventricle diastolic function and left ventricular thickness in primary hypertension patients