Zhu Xiao
2003
Citations
0
Influential Citations
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Citations
Quality indicators
Journal
Academic Journal of Second Military Medical University
Abstract
Objective: To study the effects of misoprostol and carboprost methylate on human preadipocyte proliferation and differentiation. Methods: Misoprostol and carboprost methylate were added to the culture media of human preadipocytes, then the proliferation of cells, the expression of glycerophosphate dehydrogenase(GPDH) and lipid droplet accumulation in cytoplasm during differentiation were recorded. Results: Misoprostol boosted human preadipocyte proliferation, GPDH upregulation and lipid accumulation during differentiation. Carboprost methylate enhanced misoprostol's effects. Conclusion: Application of misoprostol in combination with carboprost methylate in fat tissue transplantation may enhance the viability rate.