W. Remme, J. D. de Jong, P. D. Verduow
Jul 1, 1977
Citations
0
Influential Citations
63
Citations
Quality indicators
Journal
The American journal of cardiology
Abstract
Abstract Inosine and hypoxanthine are useful markers of early myocardial ischemia in pigs. In this study the applicability of the products of adenosine triphosphate (ATP) breakdown as markers of myocardial ischemia in man was investigated in 25 patients undergoing diagnostic cardiac catheterization for suspected coronary artery disease. Pacing-induced myocardial ischemia resulted in elevated coronary sinus hypoxanthine levels only after the onset of angina in 18 patients (from 1.2 ± 0.2 μ molar [mean ± standard error of the mean] during the control period to 2.4 ± 0.5 μ molar during ischemia, P