Tao Ying
2013
Citations
0
Influential Citations
0
Citations
Quality indicators
Journal
Journal of Chinese Practical Diagnosis and Therapy
Abstract
Objective To explore the effect of batifiban on platelet aggregation during and after percutaneous coronary intervention(PCI) in patients with non-ST segment elevation acute coronary syndrome(ACS).Methods Fifty-three patients with non-ST segment elevation ACS receiving PCI were administrated with batifiban(batifiban group,n=29) and placebo(placebo group,n=24) during and 24-hour after operation.The related platelet aggregation parameters were detected before administration,and 4 hours and 1 day after administration in two groups.The hemorrhage was observed in 30 days after operation.Results There was no significant difference in coagulation function indexes between two groups before operation(P0.05).The platelet aggregation rate was significantly lower and platelet aggregation inhibition rate was significantly higher in batifiban group than that in placebo group 4 hours and 1 day after operation(P0.05).There was no significant difference in hemorrhage between two groups(P0.05).Conclusion Batifiban is effective in PCI for non-ST segment elevation ACS with lower incidence of hemorrhage.