V. Long, H. Yardley
Aug 1, 1971
Citations
0
Influential Citations
6
Citations
Quality indicators
Journal
British Journal of Dermatology
Abstract
SUMMARY.— The effects of 2‐bromostearic acid, 2: 4‐dinitrophenol and menadione on the respiration of skin slices in the presence or absence of added glucose was measured. All 3 compounds depress endogeneous respiration, whereas in the presence of added substrate, 2‐bromostearic acid has no effect and 2: 4‐dinitrophenol and menadione stimulate respiration. Since cells in the upper part of the epidermis are in a giucose‐free environment, it is suggested that in vitro tests of potentially toxic substances should be performed both in the presence and in the absence of glucose.