Dong Baolin
2008
Citations
0
Influential Citations
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Citations
Quality indicators
Journal
Journal of Zhengzhou University
Abstract
Aim:To investigate the effects of Terazosin hydrochloride on plasma levels of high-sensitivity C-reactive protein(hs-CRP)and nitric oxide(NO)in patients with essential hypertension.Methods:A total of 40 normotensive control subjects and 40 patients with hypertension were collected.Plasma levels of hs-CRP and NO in normotensive subjects and in patients with hypertension were detected before and after Terazosin hydrochloride therapy for 1 month.Results:Plasma hs-CRP level was significantly higher in untreated hypertensive group compared with controls(P0.01).Significant decrease was observed for hs-CRP in hypertensive patients after antihypertensive treatment(P0.05).Plasma NO level was significantly lower in the untreated hypertensive group compared with controls(P0.01).Significant increase was observed for NO in hypertensive patients after antihypertensive treatment(P0.05).Conclusion:Terazosin hydrochloride treatment exerts anti-inflammatory effects in addition to its antihypertensive properties in hypertensive patients.