K. Koumaglo, M. Gbéassor, O. Nikabu
Dec 1, 1992
Citations
1
Influential Citations
121
Citations
Quality indicators
Journal
Planta medica
Abstract
The effects of three compounds, digitolutein (1), rubiadin 1-methyl ether (2) and damnacanthal (3) extracted from the stem bark and the roots of Morinda lucida Benth. on the growth of Plasmodium falciparum in vitro were investigated. The number of parasites (schizonts) decreased significantly in a dose-dependent manner, and 100% of inhibition was obtained with 30 to 40 micrograms of each compound tested. The IC50 values were calculated.