W. Ying
2011
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Quality indicators
Journal
Practical Pharmacy and Clinical Remedies
Abstract
Objective To observe the clinical efficiency and safety of tulobuterol patch in treatment of asthmatic children.Methods one hundred asthmatic children were randomly divided into two groups:tulobuterol patch group(n=50)and procaterol hydrochloride tablet group(n=50).The courses was 7 d.The improve rate of daytime symptoms,nocturnal symptoms,lung function and the last time of cough,wheezing,breathlessness were compared between the two groups.The adverse drug reactions were assessed as well.Results The improve rate of nocturnal symptoms,the value of morning PEF and the value of evening PEF of tulobuterol patch group were significantly higher than those of procaterol hydrochloride tablet group(P0.05).But the difference of the improve rate of daytime symptoms,the change of FEV1 and the last time of cough,breathlessness,wheezing between the two groups had no sigrificant difference(P0.05).The adverse events were prurit and rash,and they were mild and moderate.Conclusion Tulobuterol patch had a significant efficiency in treatment of bronchial asthma,especially in improving the nocturnal symptoms,and tulobuterol patch was more convenient and safer.