Yi Zou, Yu Hu, H. Liu
Sep 1, 2013
Citations
1
Influential Citations
10
Citations
Journal
Journal of Heterocyclic Chemistry
Abstract
A facile and eco-friendly approach for the synthesis of 6-amino-3-phenyl-4-aryl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitrile derivatives via four-component reaction of hydrazine, ethyl 3-oxo-3-phenylpropanoate, aldehydes, and malononitrile is described. The reaction is performed in water, without using any catalyst, and under ultrasound irradiation. The developed sonochemical-assisted multi-component reaction provides an improved and accelerated conversion when compared with conventional procedure.