V. M. Patel, K. R. Desai
Oct 1, 2005
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Journal
ChemInform
Abstract
A series of 1-[5'-(2,4-dichloro-5-fluorophenyl)-6'H-1', 3', 4'-thiadiazin-2'-yl]-4-(substituted phenyl)-3-chloro-2-oxo-azetidincs 3 and 3-[5'-(2, 4-dichloro-5-fluorophenyl)-6'H-1',3',4'-thiadiazin-2'-yl]-2-(substituted phenyl)-1, 3-thiazolidin-4-one 4 have been synthesized using environmentally benign procedure and evaluated for their antimicrobial activity. Neat reactants are subjected to microwave irradiation under solvent-free condition. The observed yields and enhancement in reaction rates are due to the solvent-free conditions coupled with microwave usage. Structures of the synthesized compounds have been elucidated on the basis of their elemental analyses and spectral data.