A. Fesenko, Ludmila A. Trafimova, Maxim O. Zimin
Nov 14, 2019
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Influential Citations
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Proceedings
Abstract
Synthesis of hardly available 2-alkylsemicarbazides and their hydrochlorides from semicarbazide hydrochloride has been developed. This general and efficient protocol is based on preparation of acetone semicarbazone, its N2-alkylation in the presence of sodium hydride, and hydrolysis under mild conditions.