T. Ibuka, H. Minakata, Yoshinori Mitsui
Oct 5, 1981
Citations
0
Influential Citations
8
Citations
Journal
Chemistry Letters
Abstract
Using 3-t-butyldimethylsilyloxy-1-cyclohexenyl methyl ketone as a starting material, a simple stereoselective synthesis of rel-(6S,7S,8S)-7-butyl-8-hydroxy-1-azaspiro[5,5]undecan-2-one, a useful intermediate for the synthesis of pharmacologically important alkaloid perhydrohistrionicotoxin, and its rel-(6R) isomer, was described.