Ye Cai, Chang-Chun Ling, D. Bundle
Mar 8, 2006
Citations
0
Influential Citations
31
Citations
Journal
Organic & biomolecular chemistry
Abstract
Sphingosine, sphinganines and phytosphingosines and their analogs were synthesized by an aldol condensation between an iminoglycinate bearing a (+)-(1R,2R,5R)-2-hydroxy-3-pinanone group as chiral auxiliary and an appropriate aldehyde. All condensations proceeded with excellent enantioselectivity to generate the (2S,3R)-D-erythro structures in good yields.