T. Arai, Ming-Rong Zhang, M. Ogawa
Feb 1, 2009
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Influential Citations
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Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine
Abstract
[1-(11)C]Acetyl chloride ([(11)C]AcCl), an important [(11)C]acylating agent, was synthesized by reacting [(11)C]CO(2) with methylmagnesium bromide coated on the inner surface of a polyethylene loop (loop method). By optimizing the reaction conditions and synthesis parameters, [1-(11)C]phenylacetate and [1-(11)C]benzylacetate were produced from [(11)C]AcCl in high radiochemical yield and specific activity.