A. Vidal, J. Madelmont, E. Mounetou
Feb 1, 2006
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0
Influential Citations
15
Citations
Journal
Synthesis
Abstract
A straightforward synthesis of methyl 3,4-dihydro-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide from saccharin sodium salt was achieved in five steps. Methyl 3,4-dihydro-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide found application as a precursor for the synthesis of a new class of quaternary ammonium derivatives that are potential antiosteoarthritis.