E. Menteşe, F. Yılmaz, F. Islamoglu
Apr 1, 2015
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0
Influential Citations
5
Citations
Journal
Journal of Chemical Research
Abstract
A new series of 2-aryl-5-fluoro-6-(4-phenylpiperazin-1-yl)-1H-benzimidazoles was synthesised from the reaction of 4-fluoro-5-(4-phenylpiperazin-1-yl)benzene-1,2-diamine and iminoester hydrochlorides. 4-Fluoro-5-(4-phenylpiperazin-1-yl)benzene-1,2-diamine was prepared from the reduction of 5-fluoro-2-nitro-4-(4-phenylpiperazin-1-yl)aniline by using Pd/C (10%) catalyst and hydrazine hydrate under microwave irradiation. The structures of newly synthesised compounds were identified by 1H NMR, 13C NMR, mass spectroscopy and elemental analysis data.