K. Srinivas, C. Nair, S. Ramesh
Mar 1, 2004
Citations
0
Influential Citations
9
Citations
Journal
Synthesis
Abstract
A rapid, efficient, cost effective procedure has been developed for the synthesis of 2-hutyl-5-chloro-3H-imidazole-4-carboxaldehyde. Preparation of methyl pentanimidate was accomplished in just 12 hours, followed by a sequence of reactions without isolation and purification of the formed intermediates. The final compound was purified by simple acid-base treatment to get a product with 99.9% HPLC purity.