P. S. Swaroop, S. Tripathy, Gorakhnath R. Jachak
Aug 20, 2014
Citations
0
Influential Citations
7
Citations
Journal
Tetrahedron Letters
Abstract
Abstract Both the isomers methyl-(2 S ,8 R )-2-(( tert -butoxycarbonyl)amino)-8-hydroxydecanoate and methyl-(2 S ,8 S )-2-(( tert -butoxycarbonyl)amino)-8-hydroxydecanoate of an unusual amino acid residue and the key fragment of microsporin B are prepared. The key steps include cross metathesis and enzymatic kinetic resolution. In addition, a linear tetrapeptide with desired components towards total synthesis is also reported.